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Related to hypobetalipoproteinemia: abetalipoproteinemia, Tangier disease
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Noun1.hypobetalipoproteinemia - a hereditary disorder characterized by low levels of beta-lipoproteins and lipids and cholesterol
abetalipoproteinemia - a rare inherited disorder of fat metabolism; characterized by severe deficiency of beta-lipoproteins and abnormal red blood cells (acanthocytes) and abnormally low cholesterol levels
hypolipoproteinemia - any of various disorders of lipoprotein and cholesterol metabolism that result in low levels of lipoprotein and cholesterol in the circulating blood
References in periodicals archive ?
6,7) Hypobetalipoproteinemia is a specific familial condition defined by LDL-C cholesterol equal to or less than the fifth percentile.
Hepatitis C virus-associated hypobetalipoproteinemia is correlated with plasma viral load, steatosis, and liver fibrosis.
Because BAS may modestly increase TG levels and have not been studied in patients with significantly elevated TG levels (>300 mg/dL), they should not be used in these patients or in those with familial abetalipoproteinemia or genetic hypobetalipoproteinemia.
Familial hypobetalipoproteinemia is a co-dominant disorder characterized by reduced plasma levels of LDL-C.
Similarly, in The Merck Manual, when the user finds abetalipoproteinemia in the index, and presses Enter, that user is actually given the second line of the hypobetalipoproteinemia section--one line below the nonvisible title for the section.
Hypobetalipoproteinemia (HBL) is defined by plasma concentrations of TC, LDL-C, or apo B that are lower than the fifth percentile (1).
The third variant, a compound mutation (R104C/V114A) found in a French family and associated with familial hypobetalipoproteinemia, exhibits a dominant negative effect on PCSK9 secretion (29).
Familial hypobetalipoproteinemia (FHBL) is commonly caused by mutations in the apolipoprotein B gene (APOB).
Familial hypobetalipoproteinemia (FHBL, [4] OMIM 107730) is a rare autosomal codominant disorder of lipoprotein metabolism in which sequence variations in the apolipoprotein B (APOB) [5] gene lead to decreased plasma concentrations of total cholesterol, LDL-cholesterol, and apolipoprotein (apo) B (below the 5th percentile for age and sex) (1-3).