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hypoglycaemic agent

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ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.hypoglycaemic agent - any of various agents that decrease the level of glucose in the blood and are used in the treatment of diabetes mellitus
Orinase, tolbutamide - sulfonylurea; an oral antidiabetic drug (trade name Orinase) used in the treatment of adult-onset diabetes mellitus
insulin - hormone secreted by the isles of Langerhans in the pancreas; regulates storage of glycogen in the liver and accelerates oxidation of sugar in cells
agent - a substance that exerts some force or effect


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Individuals with Type A insulin resistance who develop frank diabetes require large doses (>200 units/day) of subcutaneous insulin, oral hypoglycaemic agents and insulin sensitizers and despite this intense regimen glycemic control remains poor and these patients are at high risk of the complications of diabetes, such as cardiovascular disease, nephropathy, retinopathy and neuropathy.
Even after administration of hypoglycaemic agents such as tolbutamide, little change in blood glucose levels is seen (2).
 
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