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hypothalamic |
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| When Yanagisawa's team examined gene activity in these animals' brains, they found that genes in a region called the dorsomedial hypothalamic nucleus (DMH) cycled on and off rhythmically during the day. Postoperative endocrine evaluation revealed no hypothalamic dysfunction, and the patient was able to bottle-feed without any signs or symptoms of respiratory distress or nasal airway obstruction. Indeed, chronic lead exposure is known to interfere with hypothalamic and pituitary function as reflected by, for example, dopamine concentrations (Kala and Jadhav 1995) and signaling between the hypothalamus and the pituitary gland (Sokol et al. |
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