immune globulin


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immune globulin

n. Abbr. IG
A preparation containing gamma globulins (chiefly immunoglobulin G) obtained from blood plasma pooled from many individuals and used to confer passive immunity against various diseases such as tetanus and hepatitis B and for treatment of a variety of inflammatory and autoimmune diseases. Also called gamma globulin, immune serum globulin.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.immune globulin - a class of proteins produced in lymph tissue in vertebrates and that function as antibodies in the immune response
gamma globulin, human gamma globulin - a plasma protein containing the immunoglobulins that are responsible for immune responses
antibody - any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response
IgA, immunoglobulin A - one of the most common of the five major classes of immunoglobulins; the chief antibody in the membranes of the gastrointestinal and respiratory tracts
IgD, immunoglobulin D - one of the five major classes of immunoglobulins; present in blood serum in small amounts
IgE, immunoglobulin E - one of the five major classes of immunoglobulins; present primarily in the skin and mucous membranes
IgG, immunoglobulin G - one of the five major classes of immunoglobulins; the main antibody defense against bacteria
IgM, immunoglobulin M - one of the five major classes of immunoglobulins; involved in fighting blood infections and in triggering production of immunoglobulin G
tetanus immune globulin, tetanus immunoglobulin - sterile solution of globulins derived from the blood plasma of a person who has been immunized for tetanus; provides short-term immunization against tetanus in cases of possible exposure to the tetanus bacillus
References in periodicals archive ?
The new formulation is twice the potency (300 IU/mL) of currently available rabies immune globulin options, offering a greater concentration of anti-rabies virus antibodies within each mL of volume, and the potential for fewer injections.
The company said the new higher formulation of its HyperRAB rabies immune globulin [human] is twice the potency of 300 IU/ml, which is the available rabies immune globulin options for rabies postexposure prophylaxis (treatment of a person immediately after exposure to the rabies virus).
About Octagam 10% Octagam 10% is an immune globulin intravenous (human) liquid preparation indicated for the treatment of chronic immune thrombocytopenic purpura (ITP) in adults.
RI-002 is a specialty plasma-derived, polyclonal, intravenous immune globulin (IGIV).
Description: Stony Brook University Hospital proposes to purchase IV Immune Globulin,
serving patients requiring subcutaneous immune globulin and IV Immune globulin (IVIG) for autoimmune and primary immune deficiency diseases.
Developing an infection was not linked to gestational age, birth weight, or timing of the vaccine or immune globulin (within or after 12 hours of birth).
As the first step in a comprehensive review and evaluation of current options for updating policies for weak D testing and administration of Rh immune globulin in women with a weak D phenotype, the CAP TMRC conducted a survey in 2012, repeating the questions of the 1999 survey.
Studies conducted in the late 1960s indicated that clinical varicella was prevented in susceptible, healthy children by administration of zoster immune globulin (ZIG) (prepared from patients recovering from herpes zoster) within 72 hours of household exposure (4).
As an alternative to HRIG, equine immune globulin derived from horse serum is used in many parts of the world, but it is also scarce, expensive and can carry significant side effects.
The objective of this investigation, conducted in Almaty, Kazakhstan, was to compare the relative effectiveness of hepatitis A vaccine with that of immune globulin for prophylaxis after exposure to the hepatitis A virus.

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