immunoglobulin

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Related to immunoglobulin genes: Antibody genes

im·mu·no·glob·u·lin

 (ĭm′yə-nō-glŏb′yə-lĭn, ĭ-myo͞o′-)
n. Abbr. Ig
1. Any of a group of large glycoproteins, including all the antibodies that function in the vertebrate immune system, that have a structure consisting of two heavy chains and two light chains. There are five major classes of immunoglobulin isotypes: IgA, IgD, IgE, IgG, and IgM.
2. A preparation containing immunoglobulin proteins, especially immune globulin.

immunoglobulin

(ˌɪmjʊnəʊˈɡlɒbjʊlɪn)
n
(Biochemistry) any of five classes of proteins, all of which show antibody activity. The most abundant ones are immunoglobulin G (IgG) and immunoglobulin A (IgA)

im•mu•no•glob•u•lin

(ˌɪm yə noʊˈglɒb yə lɪn, ɪˌmyu-)

n.
1. any of several classes of globulin proteins that function as antibodies.
2. the fraction of the blood serum containing antibodies.
3. antibody. Abbr.: Ig
[1955–60]

im·mu·no·glob·u·lin

(ĭm′yə-nō-glŏb′yə-lĭn, ĭ-myo͞o′nō-glŏb′yə-lĭn)
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.immunoglobulin - a class of proteins produced in lymph tissue in vertebrates and that function as antibodies in the immune response
gamma globulin, human gamma globulin - a plasma protein containing the immunoglobulins that are responsible for immune responses
antibody - any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response
IgA, immunoglobulin A - one of the most common of the five major classes of immunoglobulins; the chief antibody in the membranes of the gastrointestinal and respiratory tracts
IgD, immunoglobulin D - one of the five major classes of immunoglobulins; present in blood serum in small amounts
IgE, immunoglobulin E - one of the five major classes of immunoglobulins; present primarily in the skin and mucous membranes
IgG, immunoglobulin G - one of the five major classes of immunoglobulins; the main antibody defense against bacteria
IgM, immunoglobulin M - one of the five major classes of immunoglobulins; involved in fighting blood infections and in triggering production of immunoglobulin G
tetanus immune globulin, tetanus immunoglobulin - sterile solution of globulins derived from the blood plasma of a person who has been immunized for tetanus; provides short-term immunization against tetanus in cases of possible exposure to the tetanus bacillus
Translations
imunoglobulin
immunoglobulina

immunoglobulin

[ˌɪmjʊnəʊˈglɒbjʊlɪn] Ninmunoglobulina f

immunoglobulin

nImmunglobulin nt

immunoglobulin

n inmunoglobulina (endógena)
References in periodicals archive ?
Statistically significant association between positive CD30 markers expressed in cancerous cells and monoclonality gene rearrangements in immunoglobulin genes was observed.
About MS Precise MS Precise utilizes next-generation sequencing to measure DNA mutations found in rearranged immunoglobulin genes in immune cells initially isolated from cerebrospinal fluid.
It is interesting that these lymphomas are monoclonal, although the immunoglobulin genes remain unmutated (8).
1-3) Tests by polymerase chain reaction (PCR) using DNA extracted from the specimen as a template and primers for immunoglobulin genes are probably among the more commonly ordered molecular tests.
ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile.
B lymphocytes rearrange the immunoglobulin genes starting with the heavy chains, followed by the kappa and lambda light chains.
Like all B-cell neoplasms, the B cells in LPL have clonally rearranged immunoglobulin genes.
Molecular analysis of PCBCL supports the hypothesis of an antigen-driven germinal center origin based on findings of a characteristic pattern of somatic hypermutation and the presence of intraclonal diversity in B-cell immunoglobulin genes (8).

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