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1. A biological specimen or other element that is a duplicate of the holotype.
2. Any of several classes or subclasses of immunoglobulins, such as immunoglobulins A and G, that are distinguished by differences in the amino acid sequence of the constant regions of their heavy chains. All isotypes are usually found in every individual of a species.

i′so·typ′ic (-tĭp′ĭk) adj.
i′so·ty′py (-tī′pē) n.


the presentation of statistical information in a row of diagrams using the international picture language created by Otto Neurath (1882–1945)


(ˈaɪ səˌtaɪp)

1. one of two or more separate biological populations of the same or a similar type.
2. any epitope that is common to all individuals in a species.
i`so•typ′ic (-ˈtɪp ɪk) adj.
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References in periodicals archive ?
Of these, 698 had PEL and BCG assays run on the same serum sample within 30 days of diagnosis; these results were used to assess whether the immunoglobulin isotype of the M-spike could affect the disparity between PEL and BCG results.
Among the 75 patients receiving BiovaxID in the study, 35 received BiovaxID manufactured with an IgM isotype and 40 received BiovaxID manufactured with an IgG isotype with each treatment vaccine produced to correspond with the patient's tumor immunoglobulin isotype.
The concentration of each immunoglobulin isotype was also quantified with monospecific antisera and calibrators, using the Behring Nephelometer BNA (Behring Diagnostics).
11-14) The advent of testing for the presence of different immunoglobulin isotypes has resulted in emphasis being placed on the positivity of RF and anti-CCP IgG in combination with IgA to assist in the identification of severity of disease.
The diagnosis of CVID is made by detecting a decrease in at least two immunoglobulin isotypes (IgG, IgA, or IgM) by two or more standard deviations below the mean.
Additional studies demonstrate that multi-biomarker models may be better predictors of progressive structural damage in RA than clinical measures and initial observations indicate that profiles of autoantibodies reactive to individual peptides may differ among immunoglobulin isotypes.

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