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immunologically |
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Rapid global travel could spread the disease quickly, and, unlike with the seasonal flu strains that come around every winter, our bodies are not immunologically familiar with this type of avian influenza--no one will have native defenses to ward off or minimize infection. Among the critical issues in developing new and better vaccines are the following: price per dose, speed of production, ease of production, choice of substrates to grow the virus in or to express viral antigens, cross-protection for variant strains, efficacy in general and in immunologically naive populations, safety, and acceptance by the regulatory agencies and the public. It may be it's indeed more virulent and on top of it we have a very large, immunologically naive population. |
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