immunosuppressor


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Noun1.immunosuppressor - a drug that lowers the body's normal immune response
medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease
mercaptopurine, Purinethol - a drug (trade name Purinethol) that interferes with the metabolism of purine and is used to treat acute lymphocytic leukemia
amethopterin, methotrexate, methotrexate sodium - toxic antimetabolite that limits cellular reproduction by acting as an antagonist to folic acid; used to treat certain cancers and psoriasis and rheumatoid arthritis
References in periodicals archive ?
Their low toxicity compared to most current immunosuppressor agents suggests the therapeutic interest of GPE + PR in Thl/macrophage dominant inflammatory diseases such as RA.
Rapamycin, an immunosuppressor used to inhibit transplanted organ rejection, was originally discovered as having antibiotic properties in the mid-1970s.
She had no history of immunomodulator, immunosuppressor or regular anti-inflammatory medication use.
Today it is used as an immunosuppressor to prevent organ rejection in transplant patients.
Rapamycin, first discovered in the 1970s in soil samples from the island, famous for its monoliths, is currently used as an immunosuppressor to prevent organ rejection in transplant patients.
The ATD have some immunosuppressor effects, (7-9) but it is less probable that these drugs could be active many years after discontinuation of the therapy.
Information on immunosuppression was obtained for patients with a history of cancer, organ transplants, splenectomy, HIV infection (when the CD4+ T-cell count was <200 cells/[micro]L), and immunosuppressor or steroid treatment ([greater than or equal to] 0.
FKBP12 is a 12-kd cis-transpeptidyl-prolyl isomerase that binds the immunosuppressor drug FK506, (54) is necessary for the normal gating of ryanodine receptor channel, (55) is a negative regulator of TGF-[beta] endocytosis, (56) and also is a regulator of cell cycle.
Patients with inactive UC and CD were treated with 5-ASA and 5-ASA plus the immunosuppressor azathioprine, respectively.
Psoraxine(R) is a protein-based therapy that is believed to act as an immunostimulator, rather than an immunosuppressor.
Cumulatively, these data suggest that air pollution acts as an immunosuppressor, deflating the normal host response to pathogens and, in particular, the pulmonary immune response.