indinavir


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Related to indinavir: nelfinavir, saquinavir

in·din·a·vir

 (ĭn-dĭn′ə-vîr)
n.
A protease-inhibiting drug given in the form of its sulfate, used usually in combination with other drugs to suppress the replication of HIV.

[Alteration of inde(ne) + -navir, protease inhibitor suffix (from saquinavir).]

indinavir

(ɪnˈdɪnəˌvɪə)
n
(Pharmacology) pharmacol a protease inhibitor which acts as an antiretroviral and is used to treat AIDS
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.indinavir - a protease inhibitor (trade name Crixivan) used for treating HIV
protease inhibitor, PI - an antiviral drug used against HIV; interrupts HIV replication by binding and blocking HIV protease; often used in combination with other drugs
Translations

indinavir

n indinavir m
References in periodicals archive ?
A study published in the journal BMJ Open Diabetes Research and Care identifies the specific drugs as stavudine or first-generation ARVs including nelfinavir or indinavir.
Ingrown toenail and paronychia have been reported secondary to drugs, such as indinavir and indinavir / ritonavir combination.
1 h before administration of tacrolimus), group 3 (pretreated with indinavir 10 mg/kg, i.
The protease inhibitors indinavir and ritonavir have shown in vitro and in vivo inhibitory effects against Candida albicans.
The company offers protease inhibitors such as ritonavir, darunavir, saquinavir, amprenavir, lopinavir, atazanavir, indinavir and tipranavir.
Presentamos el caso de un paciente masculino de 36 anos, con antecedente de infeccion por virus de inmunodeficiencia humana (VIH) e hipertension arterial, con enfermedad renal cronica (ERC) secundaria a toxicidad renal por indinavir diagnosticada en el ano 2002 que progresa a estado 5, requiriendo hemodialisis durante cuatro anos, llevado a trasplante renal con donante vivo en el Hospital Universitario San Ignacio (HUSI) en junio de 2007.
For example, one study found that supplementation with 1000 mg per day of vitamin C decreased plasma indinavir concentrations in patients receiving indinavir as a component of HAART.
21,22) Kopp et al (23) reported crystalluria in 20% of patients on indinavir and urologic symptoms in 8%.
Because depression is common among patients with HIV, my colleagues and I evaluated the pharmacokinetic effects of indinavir on venlafaxine and venlafaxine on indinavir to determine if venlafaxine would be safe to use in a patient taking a PI because of potential cytochrome P450 (CYP450) drug interactions in both classes of medications.
It is now known that the use of St John's wort may reduce the levels of anti-HIV medication, namely indinavir, among patients with Aids.
1-4) In a review of 79 cases of indinavir overdose the authors concluded that side-effects of overdose, whether acute or chronic, were generally consistent with the safety profile of the drug.
They include AZT (also known as Retrovir), 3TC (lamivudine or Epivir) and indinavir.