indoxyl


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indoxyl

(ɪnˈdɒksɪl)
n
(Elements & Compounds) a yellow water-soluble crystalline compound occurring in woad as its glucoside and in urine as its ester. Formula: C8H7NO. See also indican
[C19: from indigo + hydroxyl]
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References in periodicals archive ?
Indoxyl sulfate is a class of albumin-bound uremic toxin that cannot be cleared by MHD.
By adding a sugar molecule, the indoxyl is turned into indican -- a precursor of indigo.
Once absorbed systemically, hepatocytes convert these into indoxyl sulfate, p-cresol sulfate and triethylamine-N-oxide (Stubbs JR, 2016 & Missailidis C, 2016).
Indoxyl sulfate, a valuable biomaker in chronic kidney disease and dialysis.
The indoxyl that is liberated combines with a diazonium salt in order to produce a violet coloured azole dye.
Upon obtaining the colonies, the biochemical tests including catalase, Indoxyl acetate hydrolysis were used and in order to differentiate between the two species Jejuni and Coli hippurate hydrolysis test was conducted, which was positive for Jejuni (1).
However in our laboratory setup, histochemical staining for enzymes such as alkaline phosphatase, phosphorylase, succinic dehydrogenase, indoxyl esterase, and acid phosphatase was not available; they were not performed.
The pathogenesis begins with the metabolism of tryptophan to indole, which is absorbed and detoxified to indoxyl sulfate (liver), and finally excreted by bacteria with sulfatase and/or phosphatase that metabolize indoxyl to indirubin (red) and indigo (blue) (3).
Klotho protects against indoxyl sulphate-induced myocardial hypertrophy," Journal of the American Society of Nephrology, vol.
Tyrian purple is generated from indoxyl sulfate precursors in the hypobranchial glands of Muricidae (Baker & Sutherland 1968).
This latest extension of the concept, described in an article published in Angewandte Chemie (Applied Chemistry) encapsulated two highly unstable agents--acetylcholinesterase and indoxyl acetate--as tablets in a robust assay kit for detecting pesticides in soil or water.
The method provided possibility to identify and quantify different uremic toxins in the serum and in the spent dialysate (uric acid, hypoxanthine, indoxyl sulfate, indole-3-acetic acid, hippuric acid, etc.