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infliximab

   Also found in: Medical, Wikipedia 0.03 sec.
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Noun1.infliximab - a monoclonal antibody (trade name Remicade) used to treat Crohn's disease and rheumatoid arthritis; administered by infusion; use and dosage must be determined by a physician
monoclonal, monoclonal antibody - any of a class of antibodies produced in the laboratory by a single clone of cells or a cell line and consisting of identical antibody molecules
2.infliximab - an anti-TNF compound (trade name Remicade) consisting of an antibody directed against TNF; it is given intravenously at one-month to three-month intervals; used in treatment of regional enteritis and rheumatoid arthritis
anti-TNF compound - a class of drugs that block the action of tumor necrosis factor (TNF); used in cases of rheumatoid arthritis because TNF instigates inflammation of the joints


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The drugs come in two categories: traditional disease modifying anti-rheumatic drugs (DMARDs) like methotrexate, sulfasalzine (Azulfidine), leflunomide (Arava) and hydroxychloroquine (Plaquenil); and, for those who don't respond to DMARDs, biologic agents like TNF blockers adalimumab (Humira), etanercept (Enbrel) and infliximab (Remicade), or the newer biologic
One patient who was taking infliximab for longstanding rheumatoid arthritis became infected with Cryptococcus neoformans after cleaning a cockatiel's cage the week before hospitalization (2).
Researchers are particularly interested in patients who currently are being treated with prednisone, methotrexate, leflunomide, infliximab, or etanercept.
 
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