infliximab


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Related to infliximab: methotrexate

in·flix·i·mab

 (ĭn-flĭk′sə-măb′)
n.
A chimeric monoclonal antibody that blocks the action of tumor necrosis factor and is used to treat Crohn's disease, ulcerative colitis, rheumatoid arthritis, and certain other inflammatory conditions.

[Perhaps inf(lammatory) + -li-, immunomodulator infix + -ximab (as in rituximab).]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.infliximab - a monoclonal antibody (trade name Remicade) used to treat Crohn's disease and rheumatoid arthritis; administered by infusion; use and dosage must be determined by a physician
monoclonal, monoclonal antibody - any of a class of antibodies produced in the laboratory by a single clone of cells or a cell line and consisting of identical antibody molecules
2.infliximab - an anti-TNF compound (trade name Remicade) consisting of an antibody directed against TNF; it is given intravenously at one-month to three-month intervals; used in treatment of regional enteritis and rheumatoid arthritis
anti-TNF compound - a class of drugs that block the action of tumor necrosis factor (TNF); used in cases of rheumatoid arthritis because TNF instigates inflammation of the joints
Translations

infliximab

n infliximab m
References in periodicals archive ?
Although radiographic progression in patients receiving infliximab was the same as in patients who were not on infliximab during the first year of treatment, further progression stopped during year 2 in patients on in fliximab but continued in the control group, reported Dr.
Positive one-year results show SB4 etanercept and SB2 infliximab investigational biosimilar candidates sustained comparable safety profiles observed in previously announced primary results
The patient's symptoms did not improve with the use of immunomodulators so biologic therapy with infliximab 5 mg once every eight weeks was advised.
Drug levels are only commercially available for infliximab.
Herein, we present a resistant PG lesion associated with ulcerative colitis and spondylitis which favorably responded to infliximab infusion.
Adalimumab is the second TNF blocker to be approved for ulcerative colitis; infliximab (Remicade), an intravenous TNF blocker, was previously approved for treating UC.
27), (28) There are three TNF-[alpha] inhibitors available for clinical use in the treatment of JIA: Etanercept (Enbrel), infliximab (Remicade) and adalimumab (Humira).
6) were the first to report development of psoriatic skin lesions in connection with use of infliximab and etanercept in their study in 2004 involving two patients with RA.
It found treatment of moderate to severe Crohn's disease with infliximab plus azathioprine allows more patients to achieve remission and mucosal healing than therapy with azathioprine alone.
If those don't work, doctors frequently turn to the anti-inflammatory drug infliximab (Remicade) and a slow-acting immune suppressor called azathioprine.
1,2) PCP following infliximab therapy for Crohn disease, although still uncommon, is increasing in occurrence.
The effect of being overweight did not affect the ability to achieve remission in patients receiving infliximab and combination therapy.