innate immune response


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Related to innate immune response: Adaptive immune response

innate immune response

n.
The component of the immune response that involves the innate immune system.
References in periodicals archive ?
The researchers, who analyzed more than 10,000 DNA samples from leprosy patients and healthy people in China, said their discovery highlights the important role that the innate immune response plays in the development of leprosy.
The paper, entitled "Characterization of the Adaptive and Innate Immune Response to Intravenous Oncolytic Reovirus (Dearing Type 3) during a Phase I Clinical Trial" appears online in the March 6, 2008 issue of Gene Therapy.
They reasoned that B cells would almost never encounter a bacterial cell wall or viral capsid alone; an intact cell wall would almost always also contain other molecules that activate the innate immune response as well.
Marjorie Robbins, Adam Judge, Ellen Ambegia, Catherine Choi, Ed Yaworski, Lorne Palmer, Kevin McClintock, and Ian MacLachaln of Protiva Biotherapeutics (Burnaby, BC Canada), in a paper entitled, "Misinterpreting the Therapeutic Effects of siRNA Caused by Immune Stimulation," emphasize the need for researchers to design siRNA studies that incorporate suitable controls to differentiate the disease-modulating effect of an siRNA from its ability to stimulate an innate immune response.
HEPLISAV is a Phase 3 hepatitis B vaccine that combines HBV surface antigen (HBsAg) with Dynavax's proprietary immunostimulatory sequences (ISS), which specifically target Toll-Like Receptor 9 (TLR9) to stimulate an innate immune response.
The company's novel Toll-like Receptor 9 (TLR9) agonist products are based on its proprietary immunostimulatory sequences (ISS), which are short DNA sequences that stimulate the innate immune response.
The research team used a unique mouse model of adenovirus keratitis to study the role of viral components in the cornea and determine which viral part(s) induce an innate immune response.
Vice President of Research & Development for Biothera's Healthcare Group, said, "This study's results are exciting because they show the potential for Wellmune WGP to naturally enhance the body's innate immune response to protect against and ameliorate the symptoms of something that every one of us encounters-the common cold.
Supplementation with Active Hexose Correlated Compound increases the innate immune response of young mice to primary Influenza Infection.
Vitamin D is known to be involved in the innate immune response to infection.
VSV is sensitive to the innate immune response, which causes lymphocytes to release interferon and protect the body from developing an infection.
VTX-2337 is the first selective TLR8 compound to reach the clinic and we are hopeful that modulation of the innate immune response will provide a benefit to patients in a number of oncology indications," said Dr.