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intravital |
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| We assessed pulmonary inflammation and damage by measuring bronchoalveolar lavage (BAL) parameters and evaluated systemic microvascular function by intravital microscopy of spinotrapezius muscle arterioles. Studies using intravital microscopy, laser Doppler flowmetry, and microcast techniques have demonstrated reduced cochlear blood flow, decreased red blood cell velocity, capillary constriction, and increased vascular permeability during noise exposure. AngioSPARK(TM)680 is a nanoparticle probe that enables ultra-long and ultra-bright fluorescent imaging of vascularity and angiogenesis, specifically tailored for applications in intravital microscopy. |
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