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intron |
Also found in: Medical, Encyclopedia, Wikipedia, Hutchinson | 0.01 sec. |
intron [ˈɪntrɒn] n (Life Sciences & Allied Applications / Genetics) Biochem a stretch of DNA that interrupts a gene and does not contribute to the specification of a protein Compare exon2 [from intr(agenic) (regi)on]
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The tau gene in progressive supranuclear palsy: exclusion of mutations in coding exons and exon 10 splice sites, and identification of a new intronic variant of the disease-associated H1 haplotype in Italian cases. Recent work has demonstrated that intronic mutations can have functional consequences in some genes such as p53 (Lehman et al. 5 kb downstream of the last exon, and a significant amount of intronic sequence have been examined. |
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