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1. Impossible to resist: an irresistible impulse to sneeze.
2. Having an overpowering appeal: irresistible beauty.
3. Usage Problem Inevitable or inexorable.

ir′re·sis′ti·bil′i·ty, ir′re·sis′ti·ble·ness n.
ir′re·sis′ti·bly adv.
Usage Note: The word irresistible is sometimes used to mean "bound to happen, unstoppable, inevitable." A majority of the Usage Panel objects to this usage. In our 2006 survey, some 65 percent rejected the sentence The rise of liberal blogs was irresistible, given the broader climate of political debate.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.irresistibleness - the quality of being overpowering and impossible to resist
power, powerfulness - possession of controlling influence; "the deterrent power of nuclear weapons"; "the power of his love saved her"; "his powerfulness was concealed by a gentle facade"
References in classic literature ?
If this be so, fancy the irresistibleness of that might, to which the most impalpable and destructive of all elements contributes.