islets of Langerhans

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Related to islet cell: islets of Langerhans, Islet cell tumor

is·lets of Lang·er·hans

 (ī′lĭts; läng′ər-häns′)
pl.n.
Irregular clusters of endocrine cells scattered throughout the tissue of the pancreas that secrete insulin and glucagon. Also called islands of Langerhans.

[After Paul Langerhans (1847-1888), German pathologist.]

islets of Langerhans

(ˈlæŋəˌhæns) or

islands of Langerhans

pl n
(Anatomy) small groups of endocrine cells in the pancreas that secrete the hormones insulin and glucagon
[C19: named after Paul Langerhans (1847–88), German physician]

is·lets of Lang·er·hans

(ī′lĭts əv läng′ər-häns′)
Irregular clusters of endocrine cells that are scattered throughout the tissue of the pancreas and secrete insulin.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.islets of Langerhans - cell clusters in the pancreas that form the endocrine part of that organ; secrete insulin and other hormones
ductless gland, endocrine gland, endocrine - any of the glands of the endocrine system that secrete hormones directly into the bloodstream
pancreas - a large elongated exocrine gland located behind the stomach; secretes pancreatic juice and insulin
References in periodicals archive ?
Our study has shown that all types of islet cell have distinct and unique gene expression profiles that changes in type 2 diabetes.
Now, a new advancement from MIT, Boston Children's Hospital, and several other institutions may offer a way to fulfill the promise of islet cell transplantation.
Most patients require regular insulin injections, but some need surgical intervention--either a pancreas transplant or an islet cell transplant, in which insulin-producing islet cells from a donor pancreas are infused into the liver.
Why do islet cells fail completely in some patients--type 1 primarily --while in others with islet cell failure some have islet cells that retain some function for 50 years or more?
123 EMERGING NEW DIABETES TREATMENT STRATEGIES: BETATROPHIN VERSUS ISLET CELL TRANSPLANTATION
In a study carried out at Baylor University, researchers concerned about the poor efficacy of islet cell transplantation during pancreas preservation and islet isolation have found that low temperatures can prevent hypoxia that can damage islet cells.
Islet cell tumors are rare pancreatic or peripancreatic tumors which constitute a broad spectrum of endocrine neoplasms.
The study, which involved 154 patients with advanced pancreatic islet cell tumors, was stopped early by independent safety monitors because Sutent had demonstrated significant benefit and had met the primary goal of the trial.
Sunitinib doubles progression-free survival in pancreatic islet cell tumours
The procedure, known as an islet cell transplant, was conducted at St.
MicroIslet is working to develop and commercialize a first product, called MicroIslet-H, a microencapsulated human islet cell suspension that will be used for transplantation in patients with insulin- dependent diabetes.