isochromosome


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isochromosome

(ˌaɪsəʊˈkrəʊməˌsəʊm; ˌaɪsəʊˈkrəʊməˌzəʊm)
n
(Biology) cytology an abnormal chromosome in which the two arms share identical genetic information
References in periodicals archive ?
Believed to be critical to this transformation is the acquisition of the testicular GCT-specific isochromosome 12p, which is of uniparental origin in most cases, and is present in the vast majority of both seminomatous GCTs and NSGCTs.
De novo isochromosome 18p in a female dysmorphic child.
3) Extragonadal GCTs share the gain of isochromosome 12p with gonadal GCTs.
Monosomy 3 and isochromosome 8q in a uveal melanoma.
However strong evidence that this supernumerary is an isochromosome was given by some additional mitotic and meiotic studies, which also indicated that its heterochromatic nature is related with the amplification and dispersion of highly repetitive sequences (Mestriner et al.
Cytogenetic analysis revealed complex abnormal findings with isochromosome of 5p, rearrangement of chromosome 6, and loss of chromosomes 18 and 20 in all cells examined.
has cells with 45,X and cells with 46,XX), karyotypes with an isochromosome of X--for example i(Xq) or i(Xp)--or karyotypes with an entire or part of an Y chromosome.
8) The study revealed that subjects with isochromosome karyotype had the smallest dental crown widths when compared to the other groups.
Females with an isochromosome of the long arms of the X chromosome have larger and more frequent drumsticks, whereas females with deletions from the X chromosome have smaller drumsticks (1), (15).
double Ph, isochromosome 17q, trisomy 8 FISH analysis optional: * Only done where conventional cytogenetics not available or fails * Or, to document a BCR-ABL positivity for variant translocation and masked Ph Note: If BM material unavailable (e.
This was the irst report of what White correctly interpreted as a B isochromosome, a type of supernumerary later found in other grasshopper species (Hewitt 1973; Camacho et al.
A high incidence of isochromosome 12p in leukaemic blasts has been reported and this is a genetic abnormality found in EGCT and gonadal GCT [23].