isoenzyme


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Related to isoenzyme: isoenzyme electrophoresis

i·so·en·zyme

 (ī′sō-ĕn′zīm′)
n.
Any of several forms of an enzyme that catalyze the same reaction but differ in chemical structure. Also called isozyme.

i′so·en·zy′mic adj.

isoenzyme

(ˌaɪsəʊˈɛnzaɪm)
n
(Biochemistry) another name for isozyme
isoenzymic, isoenzymatic adj

i•so•zyme

(ˈaɪ səˌzaɪm)

n.
a variant form of certain enzymes that catalyzes the same reaction as other forms. Also called isoenzyme.
[1959; iso- + (en) zyme]
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References in periodicals archive ?
Creatine kinase isoenzyme patterns in human tissue obtained at surgery.
Bnp kit containing 1 vial of microparticles, 1 bottle of conjugate, 1 vial of diluent yield of 100 tests per kit by inmunensayo first two steps for the quantitative measurement of b-type natriuretic peptide (bnp,ck-mb kit containing 1 vial of microparticles, 1 bottle of conjugate with rendimento 100 per kit by the prince de inmunensayo two steps for the quantitative determination of isoenzyme mb of creatine kinase (ck-mb),alkaline phosphatase kit with methodology of p-nitrophenyl phosphate.
Troponin test - Creatine Kinase test - Lactate dehydrogenase - Aspartate transaminase - Myoglobin - Ischemia-modified albumin - Pro-brain natriuretic peptide - Glycogen phosphorylase isoenzyme BB The other cardiac markers are C-reactive protein, homocysteine, pulmonary embolism (D-dimer test), and high-density and low-density lipoproteins.
Characterization of the major laccase isoenzyme from Trametes pubescens and regulation of its synthesis by metal ions.
In an in vitro study of Relizen's effect on the isoenzyme CYP2D6 in pooled human liver microsomes, Dr.
Coadministering a cytochrome P450 isoenzyme 3A4 (CYP3A4)inhibiting macrolide antibiotic, such as clarithromycin or erythromycin) (but not azithromycin) with atorvastatin (Lipitor[R]), simvastatin (Zocor[R]), or lovastatin (Mevacor[R]), which are metabolized by CYP3 A4, is associated with a fourfold to 10-fold increase in statin concentrations.
Most patients received antiviral therapy, and all underwent serial electrocardiography and had blood specimens collected on days 1, 4, 11, and 28 after presentation for measurement of total creatine kinase (CK) level, CK isoenzyme MB (CK-MB) level, troponin I level, and selected cytokine levels.
Her laboratory findings revealed high levels of cardiac biomarkers [troponin I (TnI) and creatine kinase-MB isoenzyme (CK-MB)] without significant ST segment and T wave (ST-T) changes in the electrocardiogram.
The hydrolytic efficiencies of PON1 with many substrates are strongly modulated by a single nucleotide polymorphism in the PONI gene at position 192, where coding for the amino acid glutamine produces the Q isoenzyme and that for arginine produces the R isoenzyme (10).
Clarithromycin and erythromycin inhibit the cytochrome P450 isoenzyme that metabolises atorvastatin, simvastatin, and lovastatin.
ONMEL[TM], a potent cytochrome P450 3A4 isoenzyme system (CYP3A4) inhibitor, may increase plasma concentrations of drugs metabolized by this pathway.
Pharmacologically, quetiapine has antagonistic effects on serotonin 5-HT1A, 5-HT2A, dopamine D1, D2, histamine H1, and adrenergic [alpha]1, [alpha]2 receptors and it is mostly metabolized in the liver via the cytochrome p450 isoenzyme CYP3A4 (10).