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(Chemistry) (of two different molecules) having the same number of atoms and the same number and configuration of valency electrons, as carbon dioxide and nitrous oxide


(ˌaɪ səˈstɛr ɪk)

having the same number of valence electrons in the same configuration but differing in the kinds and numbers of atoms.
[1860–65; iso- + Greek ster(eós) solid + -ic]
i•sos′ter•ism, n.
References in periodicals archive ?
E]ven a change as seemingly trivial as replacing an isopropyl group with the isosteric cyclopropyl group .
Simbarashe S, Frank D, Bruno DM and AY Abel Sorption isotherms and isosteric heats of sorption of whole yellow dent corn.
Figure 7: Lead Generation Strategies and Technologies in Drug Discovery, Isosteric Replacement Form Drug-Like Hit 16
The reference stated that it was expected that the two compounds would show great similarity in properties because of the isosteric replacement of the nitrogen atom with the unsaturated carbon atom.