itraconazole


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it·ra·con·a·zole

 (ĭt′rə-kŏn′ĭ-zōl)
n.
A broad-spectrum antifungal drug, C35H38Cl2N8O4, administered orally to treat a variety of fungal infections, including blastomycosis and histoplasmosis.

[itra- (shortening and alteration of triazolo-, containing three azole groups : tri- + azole) + (mi)conazole.]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.itraconazole - an oral antifungal drug (trade name Sporanox) taken for cases of fungal nail disease
antifungal, antifungal agent, antimycotic, antimycotic agent, fungicide - any agent that destroys or prevents the growth of fungi
Translations

itraconazole

n itraconazol m
References in periodicals archive ?
Pulmatrix announced that the single dose escalation phase of the first-in-human study for Pulmazole- an inhaled iSPERSE formulation of the anti-fungal drug itraconazole for the treatment of allergic bronchopulmonary aspergillosis in patients with asthma - has commenced.
An Etest was used in accordance with the manufacturer's instructions to specify the amphotericin B (AMB), fluconazole, voriconazole, ketoconazole, itraconazole, anidulafungin, caspofungin, and flucytosine (FLU) susceptibilities of the species.
Objective: To compare the efficacy of single dose of oral itraconazole 400mg with 1% topical clotrimazole in the treatment of pityriasis versicolor.
Itraconazole and voriconazole concentrations were also inconsistent and did not reach targeted concentrations.
17%) were confirmed to be itraconazole resistant, with MICs of ≥8 mg/L, and one isolate (0.
Drug susceptibility was assessed using FUNGITEST[R] (Sanofi Diagnostics Pasteur) for the analysis of fungal growth in the presence of six drugs, such as 5-fluorocytosine, amphotericin B, miconazole, ketoconazole, itraconazole and fluconazole used at two concentrations, in modified RPMI 1640 medium, in the presence of a redox indicator.
28) was the use of pulsed itraconazole for onychomycosis.
4 Alternative therapies include itraconazole 200 mg once daily for three days.
A previous in vitro investigation found that a sinergistic effect might occur, when using itraconazole (ITRA) and ritonavir (RTV) against Histoplasma capsulatum, (1) where an interesting mechanism of action was proposed.
Treatment was instituted with oral Itraconazole, but dog died owing to severe epistaxis.
WAIKOLOA, HAWAII -- The familiar oral triazole antifungal agent itraconazole is under active investigation for an unexpected use: as adjunctive therapy in patients with locally advanced or metastatic basal cell carcinoma.
Clinically, we suspected and confirmed chromoblastomycosis based history of trauma, farmer by occupation, on hypertrophic verrucous nature of the disease, satellite lesions, black dots, sclerotic cells, elliptical conidia on LCB mount, black growth on SDA, favourable response to itraconazole and ruled out phaeohyphomycosis, mycetoma.