itraconazole


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it·ra·con·a·zole

 (ĭt′rə-kŏn′ĭ-zōl)
n.
A broad-spectrum antifungal drug, C35H38Cl2N8O4, administered orally to treat a variety of fungal infections, including blastomycosis and histoplasmosis.

[itra- (shortening and alteration of triazolo-, containing three azole groups : tri- + azole) + (mi)conazole.]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.itraconazole - an oral antifungal drug (trade name Sporanox) taken for cases of fungal nail disease
antifungal, antifungal agent, antimycotic, antimycotic agent, fungicide - any agent that destroys or prevents the growth of fungi
Translations

itraconazole

n itraconazol m
References in periodicals archive ?
Although the mainstay of treatment for central nervous system histoplasmosis remains amphotericin B, 9 of the 10 patients received itraconazole or fluconazole either as initial therapy or after a course of treatment with amphotericin B.
The patient was subsequently treated with itraconazole 200 mg administered once daily for 6 months.
Tenders are invited for Tab Itraconazole 100 Mg In Strip Packing
The IND covers HPPI's clinical development plan for a patented formulation of itraconazole (known as SUBA-Itraconazole) with improved bioavailability to study the treatment of basal cell carcinoma (BCC) in patients with basal cell carcinoma nevus syndrome (BCCNS), also known as Gorlin's syndrome, an orphan disease with no approved pharmaceutical therapy.
Itraconazole treatment was started (400 mg/d), but it was switched to amphotericin B (1 mg/kg/d) after 3 weeks because local symptoms persisted.
An open-label, evaluator-blinded study compared NOXAFIL Oral Suspension 200 mg three times daily (n=304) to fluconazole oral suspension 400 mg once daily or itraconazole oral solution 200 mg twice daily (n=298) as prophylaxis against IFIs in neutropenic patients who were receiving cytotoxic chemotherapy for AML or MDS.
The authors describe a prospective pilot study designed to investigate the use of topical nasal antifungal spray in addition to systemic steroids and itraconazole in the treatment of allergic fungal sinusitis.
Regimens include a single 150-mg dose of fluconazole or, off label, 200 mg of itraconazole b.
In a Phase 2 pilot study, Itraconazole topical suspension was shown to be effective in the treatment of FOE with no adverse events reported.
Researchers compared the pharmacokinetics and potency of itraconazole against two other antifungal compounds -- amphotericin B and voriconazole -- following intratracheal instillation in rats at doses of up to 1.
For example, there is increasing interest in using the approved antifungal medicine itraconazole (Sporanox) as a treatment for cancer.