kinetochore


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Related to kinetochore: centrosome

ki·net·o·chore

 (kə-nĕt′ə-kôr′, -nē′tə-, kī-)
n.
Either of two submicroscopic attachment points for chromosomal microtubules, present on each centromere during the process of cell division.

[kineto- + Greek khōros, place; see -chore.]

kinetochore

(kɪˈnɛtəˌkɔː; kɪˈniːtəˌkɔː; kaɪˈnɛtəˌkɔː; kaɪˈniːtəˌkɔː)
n
(Genetics) a centromere, a protein structure found in chromosomes

ki•ne•to•chore

(kɪˈni təˌkɔr, -ˌkoʊr, -ˈnɛt ə-, kaɪ-)

n.
a structure on the chromosome, at or near the centromere, to which spindle fibers attach during cell division.
[1930–35; < Greek kīnetó(s)]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.kinetochore - a specialized condensed region of each chromosome that appears during mitosis where the chromatids are held together to form an X shape; "the centromere is difficult to sequence"
anatomical structure, bodily structure, body structure, complex body part, structure - a particular complex anatomical part of a living thing; "he has good bone structure"
chromosome - a threadlike strand of DNA in the cell nucleus that carries the genes in a linear order; "humans have 22 chromosome pairs plus two sex chromosomes"
References in periodicals archive ?
Kinetochore analysis of MN from all groups revealed only an insignificant increase in the kinetochore-positive MN compared with unexposed control cells (data not shown).
has been postulated that chemicals inducing crosslinks (DNA:DNA and/or DNA:protein) increase the probability of chromosomal nondisjunction, possibly through disturbances in recombination or kinetochore and microtubule perturbations during cell division (7,17).
The CENP-A deposition machinery is recruited to centromeres in a cell cycle-regulated manner by inner kinetochore proteins associated with CENP-A, most notably CENP-C.
8226; Ready-To-Use Vectors for Live Cell Imaging of Nuclear Proteins - Coding for Kinetochore, Chaperone, Histone, Mitotic Checkpoint, Mis12 Complex, and Hec1 Complex Proteins
Induction of kinetochore-positive and kinetochore -negative micronuclei in CHO cells by ELF magnetic fields and or X-rays.
The arrangement of kinetochore activity along the whole chromosome has consequences for meiosis and must be considered in relation to function and evolution of the genome.
The centromere is the chromosomal domain that directs the formation of the kinetochore, a proteinaceous structure that interacts with the spindle microtubules to ensure proper chromosmal segregation.
The Caenorhabditis elegans kinetochore reorganizes at prometaphase and in response to checkpoint stimuli.
Likewise, within the paired kinetochores, one kinetochore represents the plus face (depicted in black in Figures 1 and 2), while the other represents the minus face (shown in red).
The conserved kinetochore protein shugoshin protects centromeric cohesion during meiosis.
This control can be disrupted by interfering with DNA repair, kinetochore assembly, checkpoints, centrosome duplication, microtubule dynamics and numerous other cellular maintenance processes (42).
Holocentric chromosomes exhibit kinetochore along the major part of their length.