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kuru |
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Outbreaks of prion disease include an epidemic of kuru among the cannibalistic Fore tribe of the New Guinea highlands (9) and an epizootic of BSE in the United Kingdom, caused by feeding to cattle protein supplements derived from prion-infected cattle offal (10). Scientists have discovered that the condition, called fatal familial insomnia, arises from a genetic mutation that creates prions, the same kind of misshapen proteins that cause scrapie, mad cow disease, kuru, and Creutzfeldt-Jakob disease. It is a prion disease requiring a protein component (prion) for transmissibility, similar to kuru, bovine spongiform encephalopathy (mad cow disease), and scrapie. |
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