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lead up

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Verb1.lead up - set in motion, start an event or prepare the way for; "Hitler's attack on Poland led up to World War II"
initiate, originate, start - bring into being; "He initiated a new program"; "Start a foundation"

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Both meta-analyses focused on the strength of association between IQ at school age and either blood lead concentration measured at 2 years of age or derived measures of lead exposure, such as average blood lead up to 3 years of age, which was found to be correlated strongly with 2-year blood lead concentration.
 
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