Syringoma and associated lentiginous
compound dysplastic nevus.
Kossard S: Atypical lentiginous
junctional naevi of the elderly and melanoma.
11) Nevertheless, there are some histologic findings that may assist in the diagnosis: aggregates of lymphoid infiltrates, poor circumscription of the dermal infiltrate, subtle pleomorphism, and hyperchromasia with an associated lentiginous
freckling or lentiginous
changes, general tissue thinning, and benign or malignant neoplasia (solar keratosis, basal cell carcinoma, squamous cancer, and melanoma).
The speckled lentiginous
nevus (BLN) and Becker nevus are clinical examples of this pattern.
Bastian believes it likely they also occur in other types of melanoma having a lentiginous
12) In populations of intermediate pigmentation, such as China, (13) Japan, (14) Saudi Arabia (15) and India, (16) there is a preponderance of acral lentiginous
melanomas, predominantly on the sole of the foot.
The black population is also more likely to have advanced disease once detected since the most common type of melanoma in blacks is the aggressive acral lentiginous
Fish Slough milk-vetch (Astragalus lentiginous
While 1 study noted a possibly increased rate of S100-negative lesions among acral lentiginous
melanomas (34) and our study reports 2 S100-negative lesions arising in acral lentiginous
or amelanotic melanomas, most of our S100-negative lesions arose in superficial spreading or nodular melanomas.
All lesions then were biopsied and sent for histopathologic examination, which diagnosed 15 melanomas (10 in situ and 5 invasive melanomas) and 38 nevi (30 Clark's nevi, 4 lentiginous
nevi, and 4 congenital pattern nevi).
7) Mucosal melanomas are usually of the acral lentiginous
type, (8) and they occur most often in the nasal cavity and sinuses (table 1).