Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.leptomeninges - the two innermost layers of the meninges; cerebrospinal fluid circulates between these innermost layers
meninges, meninx - a membrane (one of 3) that envelops the brain and spinal cord
arachnoid, arachnoid membrane - the middle of the 3 meninges
pia mater - the highly vascular innermost of the 3 meninges


n. leptomeninges, las membranas más finas del cerebro; la piamadre y la aracnoide.
References in periodicals archive ?
To the Editor: Primary central nervous system lymphoma (PCNSL) is defined as lymphoma confined to the brain, spinal cord, eye, or leptomeninges.
Retinoblastoma metastasises through haematogenous dissemination, lymphatic spread, direct infiltration along the optic nerve and dispersion through the cerebrospinal fluid, after cells in the optic nerve invade the leptomeninges.
1]-weighted images, typically without contrast-enhancement in the brain parenchyma or leptomeninges.
Kadmon is conducting ongoing Phase 2 clinical trials of tesevatinib for the treatment of EGFR-mutation-positive NSCLC that has metastasized to the brain and/or the leptomeninges and for the treatment of glioblastoma.
Postmortem biopsies of the brain and meninges demonstrated a mild infiltrate of atypical lymphoid cells within the blood vessels of the leptomeninges.
A brain biopsy specimen of cerebral cortex and superficial white matter showed a moderate lymphoplasmacytic and focally histiocytic infiltrate that involved deep cortex, white matter, and leptomeninges.
Figure 2A) and (Figure 2B) reveal enhancement of the leptomeninges over the cerebellum.
It is defined as lymphoma developing in the brain, leptomeninges, spinal cord or eyes without evidence of lymphoma outside the CNS.
The disease is defined as the inflammatory process of leptomeninges (visceral layer, pia mater and arachnoid membrane) and brain parenchyma with exudates in the subarachnoid space and surrounding brain structures.
Its histopathologic features, particularly the abundance of reticular fibers, lead to the assumption that it stems from superficially located astrocytes, affecting the leptomeninges but not the dura mater.
Meningiomas are benign tumors of the central nervous system (CNS), which arise from leptomeninges.
Nakanishi, "Age-dependent responses of glial cells and leptomeninges during systemic inflammation," Neurobiology of Disease, vol.