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leukotriene

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
leu·ko·tri·ene  (lk-trn)
n.
Any of several lipid compounds that contain 20 carbon atoms, are related to prostaglandins, and mediate the inflammatory response.
[leuko(cyte) + triene, a compound containing three double bonds (tri- + -ene).]
leukotriene [ˌluːkəʊˈtraɪiːn]
n
(Life Sciences & Allied Applications / Biochemistry) one of a class of products of metabolic conversion of arachidonic acid; the active constituents of slow-reacting substance, responsible for bronchial constriction, contraction of smooth muscle, and inflammatory processes
[from leukocyte, in which they were discovered + triene from the conjugated triene unit that they contain]
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In the group of patients who adhered to their medication, those taking leukotriene modifiers-oral asthma controllers-were more likely to have an emergency room or inpatient physician visit, less likely to use six or more short-acting beta agonist canisters and incurred higher annual costs.
Oral asthma controllers more effective than inhalers by Asian News International
These categories include the following types of drugs: corticosteroids, beta-2 agonists, anticholinergic bronchodilators, methylxanthines, leukotriene modifiers, immunomodulators and mast cell stabilizers.
Asthma medications by Wojciechowski, Bill / FOCUS: Journal for Respiratory Care & Sleep Medicine
The Food and Drug Administration has called on manufacturers of leukotriene inhibitors to include safety precautions on their drugs' labeling, because of reports of neuropsychiatric events in patients taking these drugs.
Agency calls for warnings on leukotriene inhibitors by Bullock, Lorinda / Clinical Psychiatry News
 
 
 
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