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ligase

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
li·gase  (lgs, -gz)
n.
Any of a class of enzymes that catalyze the linkage of two molecules, generally utilizing ATP as the energy donor. Also called synthetase.

[Latin ligre, to bind; see leig- in Indo-European roots + -ase.]

ligase [ˈlaɪˌgeɪz]
n
(Life Sciences & Allied Applications / Biochemistry) any of a class of enzymes that catalyse the formation of covalent bonds and are important in the synthesis and repair of biological molecules, such as DNA


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We have also observed stable interaction between NEIL2 and other BER proteins DNA polymerase beta (Pol beta), DNA ligase IIIalpha (Lig IIIalpha) and XRCC1.
It forms repair complexes with poly(ADP-ribose) polymerase (22, 23), DNA polymerase- (24, 25), DNA ligase III (26), human apurinic/apyrimidinic endonuclease (27), and proliferating cell nuclear antigen at DNA replication foci to facilitate SSB repair during S phase (28).
To discern the potential mechanisms underlying this differential loss, the levels and the activities of gamma-glutamylcysteine ligase (GCL) and cysteine availability were determined.
 
 
 
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