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ligase

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
li·gase  (lgs, -gz)
n.
Any of a class of enzymes that catalyze the linkage of two molecules, generally utilizing ATP as the energy donor. Also called synthetase.
[Latin ligre, to bind; see leig- in Indo-European roots + -ase.]
ligase [ˈlaɪˌgeɪz]
n
(Life Sciences & Allied Applications / Biochemistry) any of a class of enzymes that catalyse the formation of covalent bonds and are important in the synthesis and repair of biological molecules, such as DNA


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The presence of tuberculous bacilli was confirmed by ligase chain reaction (LCR) assay.
Coexistent cervical tuberculosis and metastatic squamous cell ... by O'Dwyer, Tigh / Ear, Nose and Throat Journal
superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, [gamma]-glutamate cysteine ligase, glutathione S-transferase, NADPH quinone oxidoreductase, heme oxygenase 1) via a genetic response pathway that acquires transcriptional activation of the antioxidant response element (ARE) by the transcription factor nuclear regulatory factor 2 (Nrf2) (Li et al.
How exposure to environmental tobacco smoke, outdoor air pollutants, ... by Rogers, Christine A. / Environmental Health Perspectives
Five microliters of DNA digest was used in a ligation reaction containing 130 [micro]g/mL Bg/II adaptor-oligonucleotide and 13 [micro]g/mL Csp6I adaptor-oligonucleotide (Invitrogen) (14), 10x T4 DNA ligase buffer, T4 DNA ligase (1 U/[micro]L) (Amersham Pharmacia), and TAC-buffer in a final volume of 20 [micro]L.
Helicobacter pullorum in Chickens, Belgium by Haesebrouck, Freddy / Emerging Infectious Diseases
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