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ligase
(redirected from ligase chain reaction)

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
li·gase  (lgs, -gz)
n.
Any of a class of enzymes that catalyze the linkage of two molecules, generally utilizing ATP as the energy donor. Also called synthetase.

[Latin ligre, to bind; see leig- in Indo-European roots + -ase.]

ligase [ˈlaɪˌgeɪz]
n
(Life Sciences & Allied Applications / Biochemistry) any of a class of enzymes that catalyse the formation of covalent bonds and are important in the synthesis and repair of biological molecules, such as DNA


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Results of tests for Neisseria gonorrhoeae and Chlamydia trachomatis by ligase chain reaction (LCx; Abbot Laboratories, Vienna, Austria) were negative.
Ligase Chain Reaction (LCR): A technique for the detection of any defined DNA sequence by amplification of ligation products complementary to the target sequence.
 
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