lipoic acid

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li·po·ic acid

 (lĭ-pō′ĭk)
n.
An organic acid, C8H14S2O2, that is essential for decarboxylation of pyruvate to acetyl coenzyme A during aerobic metabolism. It is also used as a dietary supplement for its antioxidant properties.

lipoic acid

n
(Biochemistry) biochem a sulphur-containing fatty acid, regarded as an element of the vitamin B complex, minute amounts of which are required for carbohydrate metabolism
References in periodicals archive ?
Molecular characterization of lipoamide dehydrogenase gene in Trypanosoma cruzi populations susceptible and resistant to benznidazole.
In that study 3 SNPs in creatine kinase, muscle (CKM), pyruvate dehydrogenase lipoamide kinase isozyme 4 (PDK4) and cytochrome c oxidase, subunit 4, isoform 2 (COX4I2) genotype frequency distributions were significantly (P<0.
SIRT4 is also a lipoamidase that hydrolyzes the lipoamide cofactors from the E2 component of the pyruvate dehydrogenase (PDH) complex, which reduces the activity of the complex [142].
The result was supported by Reed (1973), who thought that lipoamide dehydrogenase was the flavoprotein component of the a-keto acid, and which was involved in Krebs cycle promoting energy metabolism.
Trypanothione reductase is a member of FAD-dependent NADPH oxidoreductase protein family and shares close structural similarities with GR, lipoamide dehydrogenase and eukaryotic TrxRs (5).
Molecular basis of lipoamide dehydrogenase deficiency in Ashkenazi Jews.