In this study, Se-supplemented rats had higher liver triglyceride contents, which may provide a possible explanation for the lipogenic
effects of diets high in Se.
Effect of a high linolenic acid diet on lipogenic
enzyme activities, fatty acid composition, and meat quality in the growing pig.
We defined abnormal lipids as elevated lipids (cholesterol, triglycerides, or fatty acids) in blood or liver, increased liver weight (as surrogate measurement of hepatic steatosis), and increased activity of liver lipogenic
low-grade malignant lipogenic
neoplasm that shares some similar histologic and molecular features as SCL.
However, high CHO levels in the diets can promote fat deposition by stimulation of lipogenic
enzymes in fish liver .
Effects of dietary myo-inositol or phytic acid on hepatic concentrations of lipids and hepatic activities of lipogenic
enzymes in rats fed on corn starch or sucrose.
Enhanced lipid synthesis results from a higher expression of lipogenic
enzymes and cytokines (see table 2) that are encoded by genes regulated by two transcription factors, sterol regulatory element binding protein-1c (SREBP-1c) and early growth response-1 (Egr-1).
In situations where, for example, a person with very difficult-to-treat hypertriglyceridemia is taking a lipogenic
protease inhibitor, it may be reasonable to try switching to something else.
Wood, Effect of a High-Linolenic Acid Diet on Lipogenic
Enzyme Activities, Fatty Acid Composition, and Meat Quality in the Growing Pig, J.
Obese gene expression alters the ability of 30A5 preadipocytes to respond to lipogenic
sup] Moreover, deletion of STAT3 in myeloid cells results in markedly enhanced liver inflammation after CCl[sub]4 injection,[sup] and hepatocyte-specific STAT3 knockout mice with an ethanol-containing diet showed greater hepatic steatosis, hypertriglyceridemia, and hepatic expression of lipogenic
Also, the improved effects on fatty acid metabolism due to changed expression of a number of lipogenic
and glycolytic enzymes in the liver caused by 52--Adenosine monophosphate-activated protein kinase activation (30,31).