long-term potentiation


Also found in: Medical, Acronyms, Encyclopedia, Wikipedia.

long-term potentiation

n.
Repeated presynaptic stimulation of a nerve, either naturally or in vitro, that results in the long-lasting increased strength of a synapse and is thought to be necessary for learning and memory formation.
References in periodicals archive ?
Interaction between paired-pulse facilitation and long-term potentiation in the projection from hippocampal area CAI to the entorhinal cortex.
Long-term potentiation (LTP) increases synaptic activity, while long-term depression (LTD) reduces it.
Both NMDA and AMPA receptors are involved in regulating the synapse plasticity via long-term potentiation (LTP).
For example, various intracellular signaling mechanisms, including brain-derived neurotrophic factor (BDNF) signaling via activity-regulated cytoskeleton-associated (Arc) protein, can regulate the structural and functional components of dendritic spines associated with long-term potentiation (LTP) and synaptic plasticity (Bramham et al.
Induction and maintenance of late-phase long-term potentiation in isolated dendrites of rat hippocampal CA1 pyramidal neurones.
A synaptic model of memory: long-term potentiation in the hippocampus.
Inhaled benzo(a)pyrene impairs long-term potentiation in the F1 generation rat dentate gyrus.
Possible involvement of nitric oxide in long-term potentiation.
This project used electrophysiological field recordings to study long-term potentiation (LTP) in 22-24 month old CAM [[alpha].
Administration of agents that inhibit the enzyme phosphodiesterase (PDE) can prolong CREB activation and facilitate long-term potentiation, a strengthening of synaptic connections that may contribute to learning and memory.
Indeed, activation of leptin receptors enhances N-methyl-d-aspartic acid (NMDA) receptor function and facilitates the induction of hippocampal long-term potentiation (LTP) (1).
Full browser ?