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lovastatin |
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The NF1 mice that had received lovastatin showed brain concentrations of Ras comparable to those of the normal animals, with or without lovastatin treatment. One of these drugs, lovastatin (brand name Mevacor), was tested in the five-year Air Force/Texas Coronary Atherosclerosis Prevention Study, a study of 6,600 people middle-aged and older with slightly elevated LDLs and below normal HDLs, good cholesterol. Six statins are currently available, and they are known by a variety of brand names: atorvastatin (Lipitor*), fluvastatin (Lescol ([dagger])), lovastatin (Mevacor, ([double dagger]) Altoprev ([section])), pravastatin (Pravachol ([parallel])), rosuvastatin (Crestor (#)), and simvastatin (Zocor ([double dagger])) (2-4) (Table). |
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