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lovastatin

   Also found in: Medical, Wikipedia 0.01 sec.
lo·va·stat·in  (lv-sttn)
n.
A statin, C24H36O5, that blocks the body's synthesis of cholesterol and is administered especially to individuals at risk for heart disease.

[lo-, of unknown origin + -vastatin, statin suff.; see pravastatin.]
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.lovastatin - an oral drug (trade name Mevacor) to reduce blood cholesterol levels; used when dietary changes have proved inadequate
lipid-lowering medication, lipid-lowering medicine, statin, statin drug - a medicine that lowers blood cholesterol levels by inhibiting HMG-CoA reductase


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The NF1 mice that had received lovastatin showed brain concentrations of Ras comparable to those of the normal animals, with or without lovastatin treatment.
One of these drugs, lovastatin (brand name Mevacor), was tested in the five-year Air Force/Texas Coronary Atherosclerosis Prevention Study, a study of 6,600 people middle-aged and older with slightly elevated LDLs and below normal HDLs, good cholesterol.
Six statins are currently available, and they are known by a variety of brand names: atorvastatin (Lipitor*), fluvastatin (Lescol ([dagger])), lovastatin (Mevacor, ([double dagger]) Altoprev ([section])), pravastatin (Pravachol ([parallel])), rosuvastatin (Crestor (#)), and simvastatin (Zocor ([double dagger])) (2-4) (Table).
 
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