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n. luteoma, tumor del cuerpo lúteo.
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65) Pregnancy luteomas are associated with virilization of the mother in about 25% of cases, and female infants are virilized as well in 60% to 70% of cases.
Macroscopically, pregnancy luteomas are solid masses that may be mistaken for ovarian neoplasms because of this feature.
Pregnancy luteomas are generally thought to arise from nodular hyperplasia of theca interna cells (theca-lutein hyperplasia), (59,67,69) although others (56) have proposed an origin from stromal cells.
Pregnancy luteomas are positive for inhibin and may be positive for Melan-A, but are negative for HMB-45 and S100, which would differentiate them from malignant melanoma.