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A venous blood sample was collected and submitted for hematologic evaluation, results of which showed hemoconcentration (suspected to be the result of dehydration), anemia, and leukopenia with a slight monocytosis and lymphocytopenia (Table 1).
Only 2 patients were identified with adult-onset innate immunodeficiency (2,3); 1 patient had innate interleukin-12 receptor deficiency and 1 had idiopathic CD4 lymphocytopenia.
Idiopathic CD4 Lymphocytopenia with Cryptococcal Meningitis and Cryptococcal Abscess
Another associated entity is the selective CD4 + idiopathic lymphocytopenia syndrome, described since the 80's, which predisposes the patient to present from lung infection by atypical mycobacteria to meningeal cryptococcosis, the latter caused mostly by C.
Regarding toxicity, only one discontinuation occurred due to severe infusion reactions, but lymphocytopenia was most pronounced without infections.
Lymphocytopenia and neutrophil-lymphocyte count ratio predict bacteremia better than conventional infection markers in an emergency care unit.
Adverse events were common, affect ing 69%-92% of patients, and chiefly involved gastrointestinal complaints, flushing, and laboratory abnormalities such as elevated liver enzymes (up to 62%), eosinophilia (up to 46%), and lymphocytopenia (up to 38%).
Thrombocytopenia (platelet count, 82 K/mcL) and lymphocytopenia (absolute lymphocyte count, 0.
sup][3] These alterations start immediately after the onset of CPB and lymphocytopenia lasts in the early postoperative days, mainly from the decrease of helper/inducer T-cells.
Idiopathic CD4 lymphocytopenia and opportunistic infection: An update.
Enhancement of the efficacy of chemotherapy with oxaliplatin plus 5-fluorouracil by pretreatment with IL-2 subcutaneous immunotherapy in metastatic colorectal cancer patients with lymphocytopenia prior to therapy.
Systemic inflammatory response also causes neutrophilia and lymphocytopenia, thus resulting in an increase in the neutrophil to lymphocyte ratio, a marker of inflammation in many diseases.