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Any of various cytokines that are released by activated lymphocytes and regulate many aspects of the immune response.

[lympho- + Greek kīnein, to move; see kinin.]


(Pathology) immunol a protein, released by lymphocytes, that affects other cells involved in the immune response


(ˈlɪm fəˌkaɪn)

any of a group of lymphocyte products that perform various disease-fighting functions, as destroying infected cells.
[1969; lympho (cyte) + -kine < Greek kīneîn to move]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.lymphokine - a cytokine secreted by helper T cells in response to stimulation by antigens and that acts on other cells of the immune system (as by activating macrophages)
cytokine - any of various protein molecules secreted by cells of the immune system that serve to regulate the immune system
interleukin - any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system
References in periodicals archive ?
It appears that abnormal T cells secrete lymphokine toxic to glomeruli.
Binding of IL-2 to the IL-2 receptor on T lymphocytes leads to cell proliferation, increased lymphokine secretion(IFNg, lymphotoxin, IL-4, IL-3, IL-5, GM-CSF), and enhanced expression of class II MHC molecules.
It affects the early phase of Tcell activation and inhibits lymphokine production.
Burton JD, Bambford RN et al; "A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukaemia line, stimulates T cell proliferation and the induction of lymphokine-activated killer cells".
Role of lymphokine and antigen in the control of specific T cell responses.
13 Glucocorticoids inhibit the lymphokine effect and monocyte chemotaxis and also block Fc receptor binding and function.
The increase in cortisol during exercise is mediated by a lymphokine, interleukin-6 (IL-6) (8).
Effect of combined therapy with lymphokine activated killer cells, interleukin 2 and specific monoclonal antibody on established B16 melanoma lung metastasis.
Some of these defector molecules, migration inhibition factor (MIF) a lymphokine, inhibit the migration of macrophages in the same culture medium [11].
Regulation of lymphokine production and human T lymphocyte activation by 1,25-dihydroxyvitamin D3.
Erythema nodosum in a patient with renal cell carcinoma treated with interleukin 2 and lymphokine activated killer cells.