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lymphokine |
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Research shows that ozone depletion also may exacerbate the effect of climate change on infectious disease as well as cause immunosuppression by altering T-cells and lymphokine production. Peptide specificity and HLA restriction do not dictate lymphokine production by allergen-specific T-lymphocyte clones. Histopathologic and immunologic studies of acute HPS patients have shown antibodies, significant CD8 and CD4 T-lymphocyte activation, and lymphokine involvement, suggesting the hypothesis that HPS is an immunopathologic response to hantavirus infection (6,7,13,17,18). |
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