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 (măk′rō-sĕf′ə-lē) also mac·ro·ce·pha·li·a (-sə-fā′lē-ə, -fāl′yə)
Abnormal largeness of the head. Also called megacephaly, megalocephaly.

mac′ro·ce·phal′ic (-sə-făl′ĭk), mac′ro·ceph′a·lous adj.


(ˌmækrəʊˈsɛfəlɪ) or less commonly


(Pathology) the condition of having an abnormally large head or skull
macrocephalic, ˌmacroˈcephalous adj


(ˌmæk roʊˈsɛf ə li)
disproportionate largeness of the skull or head.
mac`ro•ce•phal′ic (-səˈfæl ɪk) adj.

macrocephalism, macrocephaly

a condition in which the head or cranial capacity is unusually large. — macrocephalic, macrocephalous, adj.
See also: Head
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.macrocephaly - an abnormally large headmacrocephaly - an abnormally large head; differs from hydrocephalus because there is no increased intracranial pressure and the overgrowth is symmetrical
abnormalcy, abnormality - an abnormal physical condition resulting from defective genes or developmental deficiencies
References in periodicals archive ?
A 2-year-old boy presented with macrocephaly, initially suspected to be due to hydrocephalus.
Macrocephaly and frontal bossing can also be found in the first year of life, which causes the typical face appearance in patients with this disease.
The autistic population, schizophrenic and the nair population have the Neanderthal anthropometric phenotype with slanting forehead, large face, stubby nose, prominent mandibles, low 2D:4D ratio, large coarse trunk, macrocephaly and longer second toe as compared to big toe.
The Proteus syndrome: partial gingantism of the hands and/or feet, nevi, hemihypertrophy, subcutaneous tumours, macrocephaly or other skull anomalies and possible growth and visceral affections.
They associated lower numbers of DUF1220 with microcephaly, when the brain is too small and larger amounts with macrocephaly, when the brain is abnormally large.
The patient also exhibited the following physical findings: relative macrocephaly, a flat face with sparse eyebrows and long eyelashes, dysplastic ears with a preauricular skin tag on his left ear, anteverted nostrils, a long philtrum and thin upper and lower lips (Figure la).
Macrocephaly was noted in 20% of boys and 27% of girls with autism spectrum disorders and in 19% of boys and 24% of girls who were unaffected co-twins.
The findings included a mild macrocephaly, progressively restricted range of movement in all joints, lack of body weight gain (approx.
Case Report: The patient had high forehead, frontal bossing, macrocephaly, apparent hypertelorism, down-slanting palpebral fissures and a broad nasal root.
Macrocephaly, dystonia, and bilateral temporal arachnoid cysts: glutaric aciduria type 1.
Armed Forces, Buster was unfamiliar with the EFMP, but when her then-one-year-old son was diagnosed with autism spectrum disorder and macrocephaly (an abnormally large head) in October 2008, she recognized he would require intensive therapy, something enrollment in the EFMP enabled her to pursue.
of Dysmorphic features children Ear Microcephaly Macrocephaly screened anomalies 38,803 14 10 1 (9.