macrophage


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Related to macrophage: mast cell, alveolar macrophage

mac·ro·phage

 (măk′rə-fāj′)
n.
Any of various large, phagocytic white blood cells that develop from monocytes, are found in the spleen, liver, and other tissues, and have a variety of functions in the immune system including engulfing and destroying pathogens and dead cells, presenting antigens to activate lymphocytes, and releasing cytokines that mediate inflammation.


mac′ro·phag′ic (-făj′ĭk) adj.

macrophage

(ˈmækrəʊˌfeɪdʒ)
n
(Zoology) any large phagocytic cell occurring in the blood, lymph, and connective tissue of vertebrates. See also histiocyte
macrophagic adj

mac•ro•phage

(ˈmæk rəˌfeɪdʒ)

n.
a large white blood cell, occurring principally in connective tissue and in the bloodstream, that ingests foreign particles and infectious microorganisms by phagocytosis.
[< German Makrophagen (pl.) (Metchnikoff, 1887), with -phagen representing Phagozyten phagocytes; see macro-, -phage]
mac`ro•phag′ic (-ˈfædʒ ɪk) adj.

mac·ro·phage

(măk′rə-fāj′)
Any of the large white blood cells in many vertebrates that engulf and break down foreign particles and bacteria in blood or lymph. Macrophages are important in the body's defense against disease and are found mainly in the spleen, lymph nodes, and liver.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.macrophage - a large phagocytemacrophage - a large phagocyte; some are fixed and other circulate in the blood stream
histiocyte - a macrophage that is found in connective tissue
phagocyte, scavenger cell - a cell that engulfs and digests debris and invading microorganisms
Translations
makrofág
FresszelleMakrophage
マクロファージ
makrofag

mac·ro·phage

n. macrófago, célula mononuclear fagocítica;
___ migrationmigración de ___ -s.
References in periodicals archive ?
Background: Tumor growth and metastasis have been closely associated with the M2 macrophage-induced activation of tumor-associated macrophages (TAMs).
In particular, I am currently developing transgenic mice that allow both the visualization of specific macrophage subsets using fluorescence microscopy and the specific depletion of these cell populations.
Our findings support the concept of pulmonary macrophage transplantation (PMT) as the first specific therapy for children with hPAP"
This protein is called macrophage inflammatory protein-1 alpha, or MIP-1a.
We hypothesized that low levels of neovascularization would be reflected in low macrophage counts.
People have been thinking of targeting monocyte influx to treat atherosclerosis, but they need to consider macrophage proliferation as an additional or alternative approach, especially in established disease.
The macrophage blood cells were "armed" with a virus which began to replicate after reaching the cancer target.
This enzyme prevents a glycol protein found in blood serum (called Gc protein or vitamin D binding protein) from converting into Gc macrophage activating factor (Gc-MAC; macrophages identify and gobble up foreign matter, including cancer cells).
1,25 (OH)2 vitamin D inhibits foam cell formation and suppresses macrophage cholesterol uptake in patients with type 2 diabetes mellitus.
Subsequent chapters address the identification of novel myeloid cell surface receptors, identifying novel ligands, phagocytosis, genetic manipulation, macrophage activation, lipid signaling, and the secretion of matrix metalloproteinases by macrophages.
tuberculosis gins up cyclic AMP production upon entering a macrophage.

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