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macrophage

   Also found in: Medical, Encyclopedia, Wikipedia, Hutchinson 0.01 sec.
mac·ro·phage  (mkr-fj)
n.
Any of the large phagocytic cells of the reticuloendothelial system.

macro·phagic (-fjk) adj.

macrophage [ˈmækrəʊˌfeɪdʒ]
n
(Life Sciences & Allied Applications / Zoology) any large phagocytic cell occurring in the blood, lymph, and connective tissue of vertebrates See also histiocyte
macrophagic  [ˌmækrəʊˈfædʒɪk] adj

macrophage  (mkr-fj)
Any of various large white blood cells that play an essential immunologic role in vertebrates and some lower organisms by eliminating cellular debris and particulate antigens, including bacteria, through phagocytosis. Macrophages develop from circulating monocytes that migrate from the blood into tissues throughout the body, especially the spleen, liver, lymph nodes, lungs, brain, and connective tissue. Macrophages also participate in the immune response by producing and responding to inflammatory cytokines.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.macrophage - a large phagocytemacrophage - a large phagocyte; some are fixed and other circulate in the blood stream
histiocyte - a macrophage that is found in connective tissue
phagocyte, scavenger cell - a cell that engulfs and digests debris and invading microorganisms


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During the study, the research team from Spain and UK observed the effect of cigarette smoke in macrophage cell lines and human alveolar macrophages obtained from smokers and patients with COPD and found that cigarette smoke extract impaired the alveolar macrophage process.
Subsequent chapters address the identification of novel myeloid cell surface receptors, identifying novel ligands, phagocytosis, genetic manipulation, macrophage activation, lipid signaling, and the secretion of matrix metalloproteinases by macrophages.
tuberculosis gins up cyclic AMP production upon entering a macrophage.
 
 
 
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