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histiocytosis
(redirected from malignant histiocytosis)

   Also found in: Medical, Legal, Encyclopedia, Wikipedia 0.01 sec.
his·ti·o·cy·to·sis  (hst-s-tss)
n. pl. his·ti·o·cy·to·ses (-sz)
Any of several abnormal conditions characterized by the appearance of histiocytes in the blood or tissues.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.histiocytosis - a blood disease characterized by an abnormal multiplication of macrophages
blood disease, blood disorder - a disease or disorder of the blood
Hand-Schuller-Christian disease, Schuller-Christian disease - inflammatory histiocytosis associated with disturbance of cholesterol metabolism; occurs chiefly in young children and is characterized by cystic defects of the skull and diabetes insipidus


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Histiocytic neoplasms of the lymphohematopoietic system have had various names including histiocytic lymphoma, malignant histiocytosis, histiocytic medullary reticulosis, reticulum sarcoma, and malignant histiocytosis.
[FIGURE OMITTED] Conclusions Patients with infection-associated HLH usually have persistent unexplained fever, cytopenia, lymphadenopathy, and, frequently, hepatosplenomegaly and coagulopathy, causing diagnostic difficulties with malignant histiocytosis or T-cell lymphoma (2).
[14,15] The ALK/NPM reciprocal transcripts have been found in several childhood ALCLs, previously diagnosed as malignant histiocytosis, which expressed multiple myelomonocytic markers, including CD13.
 
 
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