megaloblast


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meg·a·lo·blast

 (mĕg′ə-lō-blăst′)
n.
An abnormally large immature red blood cell (erythroblast) found especially in the blood of people with certain types of anemia and often associated with vitamin B12 deficiency.

meg′a·lo·blas′tic adj.

megaloblast

(ˈmɛɡələʊˌblɑːst)
n
(Medicine) an abnormally large red blood cell precursor, present in certain types of anaemia
megaloblastic adj

meg•a•lo•blast

(ˈmɛg ə ləˌblæst)

n.
an abnormally large immature dysfunctional red blood cell found in the blood esp. of persons with pernicious anemia.
[1895–1900]
meg`a•lo•blas′tic, adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.megaloblast - abnormally large red blood cell present in pernicious anemia and folic acid deficiencymegaloblast - abnormally large red blood cell present in pernicious anemia and folic acid deficiency
erythrocyte, RBC, red blood cell - a mature blood cell that contains hemoglobin to carry oxygen to the bodily tissues; a biconcave disc that has no nucleus
References in periodicals archive ?
Megaloblastic anemia is an anemia that is characterized by the presence of precursor cells, megaloblast in the bone marrow and macrocytic red cells in the peripheral blood.
The bone marrow aspiration of megaloblastic anaemia showed numerous megaloblasts with large cells with an increased nuclear/cytoplasmic ratio, sieve-like chromatin and giant metamyelocytes (Figure B).
Diagnosis requires blood tests to look for megaloblasts and measure levels of B12 and folic acid.