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megaloblastic

   Also found in: Medical, Encyclopedia 0.01 sec.
meg·a·lo·blast  (mg-l-blst)
n.
An abnormally large nucleated red blood cell found especially in people having pernicious anemia or certain vitamin deficiencies.

mega·lo·blastic adj.
ThesaurusLegend:  Synonyms Related Words Antonyms
Adj.1.megaloblastic - of or relating to megaloblastsmegaloblastic - of or relating to megaloblasts      


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In reviewing the patient's chart, you quickly noticed the anemic blood values for hemoglobin and hematocrit, but you also noticed the red blood cell indices (MCV and MCH) suggested not the typical iron deficiency anemia (microcytosis), but a megaloblastic anemia.
Megaloblastic anemia and non-megaloblastic macrocytic anemia together form a group, called macrocytic anemia.
The cause of megaloblastic anemia is primarily a failure of DNA synthesis with preserved RNA synthesis, which result in restricted cell division of the progenitor cells.
 
 
 
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