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megaloblastic anaemia

   Also found in: Medical, Encyclopedia, Wikipedia 0.03 sec.
megaloblastic anaemia
n
(Medicine / Pathology) any anaemia, esp pernicious anaemia, characterized by the presence of megaloblasts in the blood or bone marrow
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Noun1.megaloblastic anaemia - anemia characterized by many large immature and dysfunctional red blood cells (megaloblasts) in the bone marrowmegaloblastic anaemia - anemia characterized by many large immature and dysfunctional red blood cells (megaloblasts) in the bone marrow; associated with pernicious anemia
malignant anaemia, malignant anemia, pernicious anaemia, pernicious anemia - a chronic progressive anemia of older adults; thought to result from a lack of intrinsic factor (a substance secreted by the stomach that is responsible for the absorption of vitamin B12)


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Lacking Vitamin B12 can cause Pernicious Anaemia or Megaloblastic Anaemia, with or without peripheral neuropathy.
6) CLINICAL DEFICIENCY DISEASES There are two major clinical syndromes of vitamin B12 deficiency: megaloblastic anaemia and/or disease of the nervous system, neuropathy.
12] deficiency by tetrahydrofolate: evidence in favour of the methyl-folate trap hypothesis as the cause of megaloblastic anaemia in vitamin [B.
 
 
 
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