megaloblast

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meg·a·lo·blast

 (mĕg′ə-lō-blăst′)
n.
An abnormally large immature red blood cell (erythroblast) found especially in the blood of people with certain types of anemia and often associated with vitamin B12 deficiency.

meg′a·lo·blas′tic adj.

megaloblast

(ˈmɛɡələʊˌblɑːst)
n
(Medicine) an abnormally large red blood cell precursor, present in certain types of anaemia
megaloblastic adj

meg•a•lo•blast

(ˈmɛg ə ləˌblæst)

n.
an abnormally large immature dysfunctional red blood cell found in the blood esp. of persons with pernicious anemia.
[1895–1900]
meg`a•lo•blas′tic, adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.megaloblast - abnormally large red blood cell present in pernicious anemia and folic acid deficiencymegaloblast - abnormally large red blood cell present in pernicious anemia and folic acid deficiency
erythrocyte, RBC, red blood cell - a mature blood cell that contains hemoglobin to carry oxygen to the bodily tissues; a biconcave disc that has no nucleus
References in periodicals archive ?
The bone marrow aspiration of megaloblastic anaemia showed numerous megaloblasts with large cells with an increased nuclear/cytoplasmic ratio, sieve-like chromatin and giant metamyelocytes (Figure B).
4 These megaloblasts arise because of impaired DNA synthesis followed by ineffective erythropoiesis.
Diagnosis requires blood tests to look for megaloblasts and measure levels of B12 and folic acid.