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1. A migraine.
2. often megrims A caprice or fancy.
3. megrims Depression or unhappiness: "If these megrims are the effect of Love, thank Heaven, I never knew what it was" (Samuel Richardson).
[Middle English migrem, variant of migraine; see migraine.]
n (functioning as singular)
1. archaic a fit of depression
2. (Veterinary Science) archaic a disease of horses and cattle; staggers