Conjugate vaccine against meningococci
a, c, y, w 135.
Ask your doctor for the latest vaccines for haemophilus influenza, pneumococci, and meningococci
Response Strategies against Meningitis Epidemics after Elimination of Serogroup A Meningococci
The clinical consequences of Neisseria meningitidis colonization and dissemination through the brain and peripheral microvessels are not only a result of the capacity of the survival and multiplication of meningococci
in the bloodstream.
fHBP is one of many proteins found on the surface of meningococci
and contributes to the ability of the bacterium to avoid host defenses.
2,4) In fact, before the introduction of MACV in 2010, group A meningococci
accounted for almost 80% of all cases in the meningitis belt, while in 2014, only 11,900 suspected cases and less than 1,150 deaths have been reported, which are the lowest estimates since the year 2004.
7) In addition, immunisation reduces the use of antibiotics and therewith the chance to develop antibiotic resistance of meningococci
causing invasive disease and failure of chemoprophylaxis.
Anyone between the ages of 11 and 18 is encouraged to receive the meningococcal vaccine, which protects against four types of meningococci
Adhere to national vaccination guidelines for vaccination against the following: hepatitis A and B viruses, tetanus, diphtheria, pertussis, Haemophilus influenzae type B (Hib), pneumococci and meningococci
, cholera, Japanese and tickborne encephalitis, poliovirus, rabies, encephalitis, typhoid fever, and human papillomavirus (HPV).
Common to all three pathogens mentioned above is that current vaccines are predominantly based on the polysaccharide capsule, and only prevent disease due to serotypes (or in the case of meningococci
, serogroups) contained in the vaccine.
Persistence of neurological manifestations, absence of meningococci
on CSF gram staining and presence of the eschar pointed to rickettsial etiology, with positive OX-2 titres on Weil-Felix test.