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mephenytoin

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Noun1.mephenytoin - a toxic anticonvulsant drug (trade name Mesantoin) used in the treatment of epilepsy when less toxic anticonvulsants have been ineffective
Mesantoin
anticonvulsant, anticonvulsant drug, antiepileptic, antiepileptic drug - a drug used to treat or prevent convulsions (as in epilepsy)
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Once the metabolism of dextromethorphan was established to cosegregate with that of debrisoquin and other prototype substrates of CYP2D6, it was unanimously accepted as an attractive alternative to the other phenotyping probes (15) because of its recognized safety, its worldwide availability, and its specificity to CYP2D6 since no co-inheritance between mephenytoin and dextromethorphan metabolism was found in human subjects.
Cytochrome P450 2D6 polymorphism in white Lebanese population by Saade, Sarita; Mroueh, Mohamad; Saab, Yolande / Journal of Applied Research
For instance, CYP2A6 is responsible for the main metabolism of nicotine,[22] and CYP2C19 is responsible for mephenytoin metabolism.
Perspectives in Pharmacogenetics by Kalow, Werner / Archives of Pathology & Laboratory Medicine
 
 
 
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