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 (mĕp′rō-băm′āt′, mĕ-prō′bə-)
A bitter white powder, C9H18N2O4, used as a tranquilizer, muscle relaxant, and anticonvulsant.


(məˈprəʊbəˌmeɪt; ˌmɛprəʊˈbæmeɪt)
(Pharmacology) a white bitter powder used as a hypnotic. Formula: C9H18N2O4
[me(thyl) + pro(pyl + car)bamate]


(məˈproʊ bəˌmeɪt, ˌmɛp roʊˈbæm eɪt)

a white powder, C9H18N2O4, used chiefly as a tranquilizer.
[1950–55; me (thyl) + pro (pyl) + (car)bamate]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.meprobamate - a sedative and tranquilizer (trade name Miltown and Equanil and Meprin) used to treat muscle tension and anxiety
antianxiety drug, anxiolytic, anxiolytic drug, minor tranquilizer, minor tranquilliser, minor tranquillizer - a tranquilizer used to relieve anxiety and reduce tension and irritability
References in periodicals archive ?
According to the charge sheet, prosecutors said the suspect consumed hashish, amphetamine, clonazepam, alprazolam, procyclidine and meprobamate.
Analyte Class Recovery % RSD (%) (N=4) Amphetamine Amphetamines 107% 3 MDEA 85% 4 MDMA 83% 4 Methamphetamine 102% 12 Buprenorphine Analgesics 87% 5 Tramadol 97% 9 Nordiazepam Benzodiazepines 106% 1 Temazepam 95% 2 Codeine Opiates 100% 10 Fentanyl Synthetic 100% 6 Meperidine Opiates 102% 9 Methadone 96% 2 Norfentanyl 82% 3 Normeperidine 101% 4 Propoxyphene 82% 9 Sufentanil 83% 11 Meprobamate Other 85% 7 Phencyclidine 100% 2
Of the 61 analytes spiked into these 5 samples, buprenorphine (twice), norbuprenorphine (3 times), and norhydrocodone (4 times) failed to show a fragment ion, whereas meprobamate and propoxyphene failed once each to show related protonated analyte.
When these drugs, including the tranquilizers chlorpromazine (Thorazine) and meprobamate (Miltown), gained FDA approval in the 1950s, psychiatry headed onto a new path: a biological and, unfortunately, pharmaceutical track for subduing mental symptoms.
Muscle relaxants such as cyclobenzaprine or metaxalone can be useful but carisoprodol is metabolized to meprobamate, which is a tranquilizer similar to diazepam and may wisely be avoided (Zeigler 2005).
In 1950, he and organic chemist Bernie Ludwig synthesized meprobamate, which they found had psychologically relaxing properties.
The medications mentioned prominently in 1976 included among others, Flurazepam, triazolam, chloral hydrate, amylobarbitone, methaqualone, glutethimide, pentobarbital, methyprylone, secobarbital, tryptophan, meprobamate, and the old standby, diphenhydrarnine.
Common drugs causing immune thrombocytopenia Analgesics salicylates acetaminophen phenylbutazone Antibiotics cephalothin penicillin streptomycin aminosalicylic acid rifampin novobiocin Various sulfa drugs (chlorthalidone, furosemide) Alkaloids Quinidine Quinine Sedatives, anticonvulsants methoin troxidone chlorpromazine diphenylhydantoin meprobamate phenobarbital carbamazepine Oral hypoglycemics chlorpropamide tolbutamide Heavy metals gold mercury bismuth organic arsenicals Miscellaneous chloroquine chlorothiazide insecticides
Chow later claimed that Lee was allergic to Equagesic, an analgesic containing meprobamate, aspirin and ethoheptazine.