In APOLT, since native liver is only partially replaced, metabolic defect
can be corrected with preservation of the native liver.
leading to stone formation in HSK are hypovolemia, hypercalciuria and hypocitraturia.
Insulin resistance has emerged as a key metabolic defect
leading to Type 2 diabetes and coronary artery disease (CAD)," said Christoph Buettner, MD, PhD, senior author of the study and Associate Professor of Medicine (Endocrinology, Diabetes and Bone Disease) at Mount Sinai.
These findings suggested that the metabolic defect
in our patient was a deficiency of 4-HPPD.
ADI-PEG 20 is a biologic being developed by Polaris to treat cancers carrying a major metabolic defect
that renders them, unlike normal cells, unable to make arginine internally.
LISBON -- Numerous important topics in muscle diseases including treatment of muscle metabolic defect
, muscular distrophies, exercise therapy in muscle diseases and Gene therapy were discussed by eminent neurophysicians at the 21st meeting of the European Neurological Society held at Lisbon recently.
Elevations in C3-acylcarnitines are used in the diagnosis of methylmalonic aciduria, although this metabolite is several steps removed from the metabolic defect
Over 35 babies since 1995 to date have been saved from an inherited metabolic defect
that affects the development and growth of the brain.
A dopaminergic deficit in this region therefore may produce the local metabolic defect
," they wrote.
The metabolic defect
renders the body unable to process certain fatty acids.
The set point theory holds that obesity entails a metabolic defect
that functions as a homeostatic mechanism.
Further supporting their potential for gene therapeutic applications, the secretory products from these NSCs can cross-correct a prototypical genetic metabolic defect
in abnormal neurons and glia in vitro as effectively as do murine NSCs.