leukodystrophy

(redirected from metachromatic leukodystrophy)
Also found in: Medical, Acronyms, Encyclopedia, Wikipedia.
Related to metachromatic leukodystrophy: Krabbe disease, adrenoleukodystrophy

leukodystrophy

(ˌluːkəʊˈdɪstrəfɪ)
n, pl -phies
(Pathology) pathol any of several progressive disorders characterized by the degeneration of white matter or myelin
References in periodicals archive ?
Biochemical and genetic analysis of seven Korean individuals with suspected metachromatic leukodystrophy.
Similarly, children with metachromatic leukodystrophy are prone to healthcare- and device-associated infections involving opportunistic pathogens, and frequent use of broadspectrum antibiotics may predispose the children for infection with multidrug-resistant bacteria.
Four cases were Metachromatic Leukodystrophy with imaging findings of symmetric periventricular white matter T2/FLAIR hyperintensities with one case showing the typical Tigroid pattern due to sparing of perivascular white matter.
The report provides comprehensive information on the therapeutics under development for Metachromatic Leukodystrophy (MLD), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type.
Psychiatric disturbances in metachromatic leukodystrophy.
2013) Developing therapeutic approaches for metachromatic leukodystrophy.
In total 16 patients with Wiskott-Aldrich syndrome and 10 with metachromatic leukodystrophy were treated.
An example of a few entities in this latter category include adrenoleukodystrophy, metachromatic leukodystrophy, Canavan's disease, Alexander's disease, Krabbe's disease, and sudanophilic leukodystrophy.
Metachromatic leukodystrophy (MLD) is a rare inherited neurodegenerative disorder caused by a deficiency of a lysosomal enzyme arylsulphatase A.
Characterization of urinary sulfatides in metachromatic leukodystrophy using electrospray ionization-tandem mass spectrometry.
A 9-year-old girl was admitted to our hospital with juvenile metachromatic leukodystrophy (arylsulfatase A deficiency).