This may result from a malignant infiltrative process, hypercalcemia secondary to a paraneoplastic syndrome, end stage renal disease, calcium-phosphate abnormalities caused by hyperparathyroidism or other metabolic derangements, or from a local metaplastic
process resulting from repeated trauma or a chronic inflammatory state.
In addition, Helicobacter pylon organisms may be identified in the metaplastic
foci, and rarely pancreatic and osseous metaplasia may be identified.
3) These features seen in osteoma are challenging to differentiate from other diseases of bone, including ossifying fibroma, fibrous dysplasia, and metaplastic
In addition, malignant metamorphosis in areas of leukoplakia, hyperplastic and metaplastic
changes due to chronic irritation, and exposure to carcinogenic agents are possible causes of ureteral stump tumors.
bone formation in the subcutaneous nodule of a patient with mixed connective tissue disease.
The predominant one, the metaplastic
theory, postulates that there is a common ancestor cell, and through metaplasia of the original squamous cell carcinoma, the sarcomatous component arises.
Clinicians who suspect this is the cause of a patient's discomfort will need to differentiate it from acquired distichiasis, which is metaplastic
eyelash growth that results from chronic lid inflammation.
In its most serious form, affecting about 10% of gastroesophageal reflux disease (GERD) patients, the constant reflux of acid can cause Barrett's esophagus, a metaplastic
change of the esophageal lining that is associated with the development of esophageal cancer.
In contrast to those not exposed to DEE, those who were had clear goblet cell hyperplasia with increased metaplastic
and dysplastic epithelia and an increase in leukocytes.
Still, about 50% of patients not only completely eliminate dysplasia, but actually replace the intestinal metaplastic
cells with normal esophageal squamous mucosa.
Utilizes a high-resolution display and proprietary software to provide an image that can be reviewed by a physician to identify areas of suspicion such as inflammatory, metaplastic
or dysplastic changes, or possible cancers.