A novel erythromycin resistance methylase
gene (ermTR) in Streptococcus pyogenes.
Prevalence of plasmid-mediated quinolone resistance determinants in association with [beta]-lactamases, 16S rRNA methylase
genes and integrons amongst clinical isolates of Shigella flexneri.
Worldwide disseminated armA aminoglycoside resistance methylase
gene is borne by composite transposon Tn1548.
This process undergoes deoxyadenosine methylase
(Dam) dependent methylation of GATC sequence in E.
Emergence of Klebsiella pneumoniae coproducing KPC-2 and 16S rRNA methylase
ArmA in Poland.
aureus synthesizes ribosomal methylase
, which is encoded by the erythromycin resistance gene or another methylases
Since Modrich's previous research focused on the enzyme dam methylase
, the researchers used this to add methyl groups to one of the DNA strands.
Prevalence of 16S rRNA methylase
genes among fi-lactamase-producing Enterobacteriaceae clinical isolates in Saudi Arabia.
17,20) In constitutive resistance methylase
is always produced but in case of inducible resistance methylase
is produced only in presence of inducer.
In fact, studies have shown that the resistance of Clostridium strains to this antimicrobial is primarily related to the erythromycin ribosomal methylase
(erm) genes, which encode a methylase
that inhibits erythromycin activity (SLAVIC et al.
coli suggest GidA is a tRNA modification methylase
responsible for the proper biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm5s2u) at the 5 position of the wobble uridine (U34) of tRNAs [6,7].
Hyperglycemia induces a dynamic cooperativity of histone methylase
and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail.